Synonymes distoma viverrini poirier, 1886 protonyme prevalence du cholangiocarcinome et do. Opisthorchis viverrini and clonorchis sinensis a opisthorchis viverrini thailand is the most endemic country for opisthorchiasis due to o. Opisthorchiasis is a parasitic disease that can infect fish eating mammals, including humans. The major risk factor for cca in thailand is the carcinogenic liver fluke opisthorchis viverrini ov infection. Opisthorchis viverrini, common name southeast asian liver fluke, is a foodborne trematode parasite from the family opisthorchiidae that infects the bile duct. Pdf opisthorchis viverrini and opisthorchiasis banchob. Trematodes flukes opisthorchis viverrini southeast asian liver fluke and opisthorchis felineus cat liver fluke. This study is a crosssectionalanalytic study, aimed to determine actual levels of o. Opisthorchis viverrini and clonorchis sinensis were considered by a previous iarc working group in 1994. Liver fluke infection casued by opisthorchis viverrini is a major public health problem. Opisthorchis viverrini infection, which brings to chronic inflammation. Pdf opisthorchiasis caused by opisthorchis viverrini remains a major public.
Infection with the parasite is called opisthorchiasis. Detection and discrimination of liver fluke in surin people. Pdf opisthorchis viverrini and opisthorchis felineus. Liver flukes are platyhelminth parasites of the class trematoda, and opisthorchis viverrini o viverrini is a member of the family opisthorchiidae. Worms and human disease 2nd edition ralph muller, dsc, phd, fibiol department of infectious and tropical diseases london school of hygiene and tropical medicine university of london, uk and former director international institute of parasitology st albans, hertfordshire, uk with contributions and the chapter on immunology of helminths from. Opisthorchis viverrini medigoo health medical tests and. Research highlights opisthorchis viverrini, fishborne parasite infection liver fluke.
Moreover, other mechanisms that enhance cca development are also postulated. People become infected when eating raw or undercooked fish that contains the parasite. Pdf epidemiology of opisthorchis viverrini paiboon. Opisthorchis viverrini and clonorchis sinensis biological. Opisthorchis viverriniis a food borne trematode, important because of the sheer numbers of people infected and its serious morbidities such as hepatobiliary diseases and cholangiocarcinoma. Opisthorchiasis, highly prevalent in the isan region of northeastern thailand and laos.
Infection with opisthorchis viverrini and its associated cholangiocarcinoma cca is an underestimated problem in the mekong region of southeast asia, despite the widespread use of praziquantel. In southeast asia, opisthorchiasis alone was responsible for 63,000 of years of life lost and 74,000 disabilityadjusted life years dalys. Opisthorchis viverrini ov infection is the main risk factor for cholangiocarcinoma and is often found in northeastern thailand. Morbidity assessment of opisthorchis viverrini infection in. Although infections are identified throughout southeast asia, the epicenter is northeast thailand, where high prevalence coexists with a high. After ingestion, the liver flukes grow to adult worms that live inside the human. Opisthorchis viverrini description, causes and risk factors. The three major liver trematodes flukes that infect humans are clonorchis sinensis, opisthorchis species, and fasciola hepatica. Morbidity assessment of opisthorchis viverrini infection. Morfologicamente e muito semelhante ao opistorchis felineus, embora ligeiramente menor. In 198081, the prevalence in the north, northeastern, centre. The majorities of information resources regarding prevention and control of.
In thailand and neighbouring countries, human opisthorchiasis is caused by o. Advanced periductal fibrosis from infection with the. A crosssection study was conducted using several secondary data including mortality and incidence of. Chronic infection may lead to cholangiocarcinoma, a malignant cancer of the bile ducts. The prevalence of ov infection and the incidence of. Worms and human disease shahid sadoughi university of. Opisthorchis viverrini medigoo health medical tests. The adult flukes deposit fully developed eggs that are passed in the feces. The ecology of the bithynia first intermediate hosts of.
Cholangiocarcinoma cca is still a major public health problem in thailand. Ele vive no figado humano, sendo encontrado principalmente nas vias biliares e vesicula biliar, alimentase da bile. Dicrocoelium dendriticum, the lancet liver fluke, is a parasite fluke that tends to live in cattle or other grazing mammals. Characterization of tubulin from liver fluke, opisthorchis viverrini. After the eggs hatch, infected snails will release microscopic larvae that can enter freshwater fish. The oriental liver flukes opisthorchis viverrini, opisthorchis felineus, chlonorchis sinensis are important causes of human disease. Cholangiocarcinoma, like opisthorchiasis, is highly prevalent in isan region of. Since that time, new data have become available, these have been incorporated in the monograph, and taken into consideration in the present evaluation. After ingestion by a suitable snail first intermediate host, the eggs release miracidia, which undergo in the snail several developmental stages sporocysts, rediae. Opisthorchis viverrini bithynia siamensis goniomphalos.
In 2005, the total number of individuals infected with opisthorchis spp. Opisthorchis viverrini is a food borne trematode, important because of the sheer numbers of people infected and its serious morbidities such as hepatobiliary diseases and cholangiocarcinoma chca. May 16, 2016 the oriental liver flukes opisthorchis viverrini, opisthorchis felineus, chlonorchis sinensis are important causes of human disease. Morphological study on cercarial of opisthorchis viverrini. The eggs of opisthorchis viverrini are ingested by snails in fresh water. Pdf risk factors for opisthorchis viverrini infection in. People are infected after eating raw or undercooked fish. Much of what is presently known about dicrocoelium dendriticum is the result of the work of the naturalist wendell krull. Opisthorchis infection is a known cause of cholangiocarcinoma, bile duct cancer. Clonorchis sinensis, opisthorchis viverrini and opisthorchis felineus are three closely related species that produce similar clinical manifestations in humans. The results reveal that 510 participants were 242 males and 268 females. This study aimed to investigate the cca burden attributable to ov infection using the disabilityadjustedlifeyear daly. Of 98 patients who had opisthorchiasis opisthorchis viverrini, there. Son cycle fait intervenir deux hotes intermediaires en eau douce.
O viverrini is highly prevalent in thailand and laos while c. Opisthorchis viverrini wikipedia, a enciclopedia livre. Opisthorchis viverrini an overview sciencedirect topics. Opisthorchis viverrini, adult worm image from ash, 1997. They have a knob at the abopercular end that may be prominent, inconspicuous, or absent. These pathogen safety data sheets, regulated under workplace hazardous materials information system whmis legislation, are produced for personnel working in the life sciences as quick safety reference material relating to infectious microorganisms. Gymnocephalous 72%, parapleurolophocercous 22% pleurolophocercous 6%. Characterization of tubulin from liver fluke, opisthorchis. Opisthorchis viverrini is found mainly in northeast thailand, laos, cambodia, and central and southern vietnam. Ov, is a serious health problem of northeast, thailand. Opisthorchiasis is a parasitic disease caused by species in the genus opisthorchis specifically, opisthorchis viverrini and opisthorchis felineus.